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Hsp60 (HSPD1) Mouse Monoclonal Antibody [Clone ID: LBI3A2]

Product Specifications

Background

This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq, Jun

Synonyms

CPN60; GROEL; HLD4; HSP-60; HSP60; HSP65; HuCHA60; SPG13

Gene Name

Homo sapiens heat shock protein family D (Hsp60) member 1 (HSPD1), transcript variant 2, mRNA; nuclear gene for mitochondrial product.

Gene ID

3329

UniProt

P10809

Conjugation

Unconjugated

Related Pathways

RNA degradation, Type I diabetes mellitus

Field of Research

RNA degradation, Type I diabetes mellitus

Dilution

WB 1:2000, IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Stem cell - Pluripotency

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

HSPD1

Overview

Carrier-free (BSA/glycerol-free) HSPD1 mouse monoclonal antibody, clone LBI3A2

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=3329

Uniprot URL

https://www.uniprot.org/uniprot/P10809

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