TIA1 Mouse Monoclonal Antibody [Clone ID: LBI1A3]
Product Specifications
Background
The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly (A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature. [provided by RefSeq, Jul 2008]
Synonyms
ALS26; TIA-1; WDM
Gene Name
Homo sapiens TIA1 cytotoxic granule associated RNA binding protein (TIA1), transcript variant 2, mRNA.
Gene ID
7072
UniProt
P31483
Conjugation
Unconjugated
Dilution
WB 1:2000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
TIA1
Overview
Carrier-free (BSA/glycerol-free) TIA1 mouse monoclonal antibody, clone LBI1A3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=7072
Uniprot URL
https://www.uniprot.org/uniprot/P31483
Curated Selection
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