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TIA1 Mouse Monoclonal Antibody [Clone ID: LBI1A3]

Product Specifications

Background

The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly (A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature. [provided by RefSeq, Jul 2008]

Synonyms

ALS26; TIA-1; WDM

Gene Name

Homo sapiens TIA1 cytotoxic granule associated RNA binding protein (TIA1), transcript variant 2, mRNA.

Gene ID

7072

UniProt

P31483

Conjugation

Unconjugated

Dilution

WB 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

TIA1

Overview

Carrier-free (BSA/glycerol-free) TIA1 mouse monoclonal antibody, clone LBI1A3

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=7072

Uniprot URL

https://www.uniprot.org/uniprot/P31483

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