PPT1 Mouse Monoclonal Antibody [Clone ID: LBI1F10]
Product Specifications
Background
The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4) . Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Synonyms
CLN1; INCL; PPT
Gene Name
Homo sapiens palmitoyl-protein thioesterase 1 (PPT1), transcript variant 1, mRNA.
Gene ID
5538
UniProt
P50897
Conjugation
Unconjugated
Related Pathways
Fatty acid elongation in mitochondria, Lysosome, Metabolic pathways
Field of Research
Fatty acid elongation in mitochondria, Lysosome, Metabolic pathways
Dilution
WB 1:2000, IHC 1:500
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PPT1
Overview
Carrier-free (BSA/glycerol-free) PPT1 mouse monoclonal antibody, clone LBI1F10
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5538
Uniprot URL
https://www.uniprot.org/uniprot/P50897
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