PPT1 Mouse Monoclonal Antibody [Clone ID: LBI1A10]

Product Specifications

Background

The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4) . Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

Overview

Carrier-free (BSA/glycerol-free) PPT1 mouse monoclonal antibody, clone LBI1A10

Synonyms

CLN1; INCL; PPT

Gene Name

Homo sapiens palmitoyl-protein thioesterase 1 (PPT1), transcript variant 1, mRNA.

Gene ID

5538

UniProt

P50897

Conjugation

Unconjugated

Related Pathways

Fatty acid elongation in mitochondria, Lysosome, Metabolic pathways

Field of Research

Fatty acid elongation in mitochondria, Lysosome, Metabolic pathways

Dilution

WB 1:2000, IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.