Cullin 4B (CUL4B) Mouse Monoclonal Antibody [Clone ID: LBI1C4]

Product Specifications

Background

This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) CUL4B mouse monoclonal antibody, clone LBI1C4

Synonyms

CUL-4B; MRXHF2; MRXS15; MRXSC; SFM2

Gene Name

Homo sapiens cullin 4B (CUL4B), transcript variant 1, mRNA.

Gene ID

8450

UniProt

Q13620

Conjugation

Unconjugated

Related Pathways

Nucleotide excision repair, Ubiquitin mediated proteolysis

Field of Research

Nucleotide excision repair, Ubiquitin mediated proteolysis

Dilution

WB 1:2000, IHC 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.