Cullin 4B (CUL4B) Mouse Monoclonal Antibody [Clone ID: LBI7F8]
Product Specifications
Background
This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
CUL-4B; MRXHF2; MRXS15; MRXSC; SFM2
Gene Name
Homo sapiens cullin 4B (CUL4B), transcript variant 1, mRNA.
Gene ID
8450
UniProt
Q13620
Conjugation
Unconjugated
Related Pathways
Nucleotide excision repair, Ubiquitin mediated proteolysis
Field of Research
Nucleotide excision repair, Ubiquitin mediated proteolysis
Dilution
WB 1:2000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
CUL4B
Overview
Carrier-free (BSA/glycerol-free) CUL4B mouse monoclonal antibody, clone LBI7F8
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=8450
Uniprot URL
https://www.uniprot.org/uniprot/Q13620
Curated Selection
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