Epoxide hydrolase (EPHX1) Mouse Monoclonal Antibody [Clone ID: LBI2C1]

Product Specifications

Background

Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Overview

Carrier-free (BSA/glycerol-free) EPHX1 mouse monoclonal antibody, clone LBI2C1

Synonyms

EPHX; EPOX; HYL1; MEH

Gene Name

Homo sapiens epoxide hydrolase 1 (EPHX1), transcript variant 1, mRNA.

Gene ID

2052

UniProt

P07099

Conjugation

Unconjugated

Related Pathways

Metabolism of xenobiotics by cytochrome P450

Field of Research

Metabolism of xenobiotics by cytochrome P450

Dilution

WB 1:2000, FLOW 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Protease

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.