Epoxide hydrolase (EPHX1) Mouse Monoclonal Antibody [Clone ID: LBI2C1]
Product Specifications
Background
Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Synonyms
EPHX; EPOX; HYL1; MEH
Gene Name
Homo sapiens epoxide hydrolase 1 (EPHX1), transcript variant 1, mRNA.
Gene ID
2052
UniProt
P07099
Conjugation
Unconjugated
Related Pathways
Metabolism of xenobiotics by cytochrome P450
Field of Research
Metabolism of xenobiotics by cytochrome P450
Dilution
WB 1:2000, FLOW 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Protease
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
EPHX1
Overview
Carrier-free (BSA/glycerol-free) EPHX1 mouse monoclonal antibody, clone LBI2C1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=2052
Uniprot URL
https://www.uniprot.org/uniprot/P07099
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