RFC2 Mouse Monoclonal Antibody [Clone ID: LBI3A7]

Product Specifications

Background

The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) . RFC, also called activator 1, is a protein complex consisting of five distinct subunits of 145, 40, 38, 37, and 36.5 kD. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP. Deletion of this gene has been associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]

Overview

Carrier-free (BSA/glycerol-free) RFC2 mouse monoclonal antibody, clone LBI3A7

Synonyms

RFC40

Gene Name

Homo sapiens replication factor C subunit 2 (RFC2), transcript variant 2, mRNA.

Gene ID

5982

UniProt

P35250

Conjugation

Unconjugated

Related Pathways

DNA replication, Mismatch repair, Nucleotide excision repair

Field of Research

DNA replication, Mismatch repair, Nucleotide excision repair

Dilution

WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Stem cell - Pluripotency

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.