SnoN (SKIL) Mouse Monoclonal Antibody [Clone ID: LBI2C9]
Product Specifications
Background
The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB) . In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Synonyms
SNO; SnoA; SnoI; SnoN
Gene Name
Homo sapiens SKI like proto-oncogene (SKIL), transcript variant 1, mRNA.
Gene ID
6498
UniProt
P12757
Conjugation
Unconjugated
Dilution
WB 1:500, IHC 1:150
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Transcription Factors
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
SKIL
Overview
Carrier-free (BSA/glycerol-free) SKIL mouse monoclonal antibody, clone LBI2C9
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=6498
Uniprot URL
https://www.uniprot.org/uniprot/P12757
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