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UBE2E3 Mouse Monoclonal Antibody [Clone ID: LBI3B7]

Product Specifications

Background

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]

Synonyms

UBCH9; UbcM2

Gene Name

Homo sapiens ubiquitin conjugating enzyme E2 E3 (UBE2E3), transcript variant 1, mRNA.

Gene ID

10477

UniProt

Q969T4

Conjugation

Unconjugated

Related Pathways

Ubiquitin mediated proteolysis

Field of Research

Ubiquitin mediated proteolysis

Dilution

WB 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

UBE2E3

Overview

Carrier-free (BSA/glycerol-free) UBE2E3 mouse monoclonal antibody, clone LBI3B7

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=10477

Uniprot URL

https://www.uniprot.org/uniprot/Q969T4

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