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SPG7 Mouse Monoclonal Antibody [Clone ID: LBI9F12]

Product Specifications

Background

This gene encodes a nuclear-encoded mitochondrial metalloprotease protein that is a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 7. [provided by RefSeq]

Overview

Carrier-free (BSA/glycerol-free) SPG7 mouse monoclonal antibody, clone LBI9F12

Synonyms

CAR; CMAR; PGN; SPG5C

Gene Name

Homo sapiens SPG7 matrix AAA peptidase subunit, paraplegin (SPG7), transcript variant 1, mRNA.

Gene ID

6687

UniProt

Q9UQ90

Conjugation

Unconjugated

Dilution

WB 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Protease, Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

SPG7

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=6687

Uniprot URL

https://www.uniprot.org/uniprot/Q9UQ90

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