GADD45A Mouse Monoclonal Antibody [Clone ID: LBI1C9]

Product Specifications

Background

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]

Overview

Carrier-free (BSA/glycerol-free) GADD45A mouse monoclonal antibody, clone LBI1C9

Synonyms

DDIT1; GADD45

Gene Name

Homo sapiens growth arrest and DNA damage inducible alpha (GADD45A), transcript variant 1, mRNA.

Gene ID

1647

UniProt

P24522

Conjugation

Unconjugated

Related Pathways

Cell cycle, MAPK signaling pathway, p53 signaling pathway

Field of Research

Cell cycle, MAPK signaling pathway, p53 signaling pathway

Dilution

WB 1:4000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Stem cell - Pluripotency

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.