GADD45A Mouse Monoclonal Antibody [Clone ID: LBI1C9]
Product Specifications
Background
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
Synonyms
DDIT1; GADD45
Gene Name
Homo sapiens growth arrest and DNA damage inducible alpha (GADD45A), transcript variant 1, mRNA.
Gene ID
1647
UniProt
P24522
Conjugation
Unconjugated
Related Pathways
Cell cycle, MAPK signaling pathway, p53 signaling pathway
Field of Research
Cell cycle, MAPK signaling pathway, p53 signaling pathway
Dilution
WB 1:4000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Stem cell - Pluripotency
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
GADD45A
Overview
Carrier-free (BSA/glycerol-free) GADD45A mouse monoclonal antibody, clone LBI1C9
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=1647
Uniprot URL
https://www.uniprot.org/uniprot/P24522
Curated Selection
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