DHLAG (CD74) Mouse Monoclonal Antibody [Clone ID: LBI1H3]
Product Specifications
Background
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta) . Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Synonyms
DHLAG; HLADG; Ia-GAMMA; II
Gene Name
Homo sapiens CD74 molecule (CD74), transcript variant 1, mRNA.
Gene ID
972
UniProt
P04233
Conjugation
Unconjugated
Related Pathways
Antigen processing and presentation
Field of Research
Antigen processing and presentation
Dilution
WB 1:4000, IHC 1:150
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
CD74
Overview
Carrier-free (BSA/glycerol-free) CD74 mouse monoclonal antibody, clone LBI1H3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=972
Uniprot URL
https://www.uniprot.org/uniprot/P04233
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
