DHLAG (CD74) Mouse Monoclonal Antibody [Clone ID: LBI1H3]

Product Specifications

Background

The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta) . Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]

Overview

Carrier-free (BSA/glycerol-free) CD74 mouse monoclonal antibody, clone LBI1H3

Synonyms

DHLAG; HLADG; Ia-GAMMA; II

Gene Name

Homo sapiens CD74 molecule (CD74), transcript variant 1, mRNA.

Gene ID

972

UniProt

P04233

Conjugation

Unconjugated

Related Pathways

Antigen processing and presentation

Field of Research

Antigen processing and presentation

Dilution

WB 1:4000, IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.