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Sterol carrier protein 2 (SCP2) Mouse Monoclonal Antibody [Clone ID: LBI1D2]

Product Specifications

Background

This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. [provided by RefSeq, Aug 2010]

Synonyms

NLTP; NSL-TP; SCOX; SCP-2; SCP-CHI; SCP-X; SCPX

Gene Name

Homo sapiens sterol carrier protein 2 (SCP2), transcript variant 1, mRNA.

Gene ID

6342

UniProt

P22307

Conjugation

Unconjugated

Related Pathways

Metabolic pathways, PPAR signaling pathway, Primary bile acid biosynthesis

Field of Research

Metabolic pathways, PPAR signaling pathway, Primary bile acid biosynthesis

Dilution

WB 1:4000, IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

SCP2

Overview

Carrier-free (BSA/glycerol-free) SCP2 mouse monoclonal antibody, clone LBI1D2

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=6342

Uniprot URL

https://www.uniprot.org/uniprot/P22307

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