VEGFB Mouse Monoclonal Antibody [Clone ID: LBI2C4]

Product Specifications

Background

This gene encodes a member of the PDGF (platelet-derived growth factor) /VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1) . Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011]

Overview

Carrier-free (BSA/glycerol-free) VEGFB mouse monoclonal antibody, clone LBI2C4

Synonyms

VEGFL; VRF

Gene Name

Homo sapiens vascular endothelial growth factor B (VEGFB), transcript variant VEGFB-186, mRNA.

Gene ID

7423

UniProt

P49765

Conjugation

Unconjugated

Related Pathways

Bladder cancer, Cytokine-cytokine receptor interaction, Focal adhesion, mTOR signaling pathway, Pancreatic cancer, Pathways in cancer, Renal cell carcinoma

Field of Research

Bladder cancer, Cytokine-cytokine receptor interaction, Focal adhesion, mTOR signaling pathway, Pancreatic cancer, Pathways in cancer, Renal cell carcinoma

Dilution

WB 1:4000, IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Secreted Protein

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.