Fibrinogen gamma chain (FGG) Mouse Monoclonal Antibody [Clone ID: LBI4B8]
Product Specifications
Background
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul
Synonyms
Fibrinogen; fibrinogen gamma chain; gamma chain; gamma polypeptide
Gene Name
Homo sapiens fibrinogen gamma chain (FGG), transcript variant gamma, mRNA.
Gene ID
2266
UniProt
P02679
Conjugation
Unconjugated
Related Pathways
Complement and coagulation cascades
Field of Research
Complement and coagulation cascades
Dilution
WB 1:4000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Secreted Protein, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
FGG
Overview
Carrier-free (BSA/glycerol-free) FGG mouse monoclonal antibody, clone LBI4B8
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=2266
Uniprot URL
https://www.uniprot.org/uniprot/P02679
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
