Hydroxysteroid (17 beta) Dehydrogenase 4 (HSD17B4) Mouse Monoclonal Antibody [Clone ID: LBI4F9]
Product Specifications
Background
The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD) . An apparent pseudogene of this gene is present on chromosome 8. [provided by RefSeq, Jul 2008]
Synonyms
DBP; MFE-2; MPF-2; PRLTS1; SDR8C1
Gene Name
Homo sapiens hydroxysteroid 17-beta dehydrogenase 4 (HSD17B4), transcript variant 2, mRNA.
Gene ID
3295
UniProt
P51659
Conjugation
Unconjugated
Related Pathways
Metabolic pathways, Primary bile acid biosynthesis
Field of Research
Metabolic pathways, Primary bile acid biosynthesis
Dilution
WB 1:4000, IF 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
HSD17B4
Overview
Carrier-free (BSA/glycerol-free) HSD17B4 mouse monoclonal antibody, clone LBI4F9
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3295
Uniprot URL
https://www.uniprot.org/uniprot/P51659
Curated Selection
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