IL10RA Mouse Monoclonal Antibody [Clone ID: LBI1D4]
Product Specifications
Background
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009]
Overview
Carrier-free (BSA/glycerol-free) IL10RA mouse monoclonal antibody, clone LBI1D4
Synonyms
CD210; CD210a; CDW210A; HIL-10R; IL-10R1; IL10R
Gene Name
Homo sapiens interleukin 10 receptor subunit alpha (IL10RA), transcript variant 1, mRNA.
Gene ID
3587
UniProt
Q13651
Conjugation
Unconjugated
Related Pathways
Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
Field of Research
Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
Dilution
WB 1:4000, IF 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
IL10RA
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3587
Uniprot URL
https://www.uniprot.org/uniprot/Q13651
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