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P60 CAF1 (CHAF1B) Mouse Monoclonal Antibody [Clone ID: LBI4F7]

Product Specifications

Background

Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair. [provided by RefSeq, Jul 2008]

Synonyms

CAF-1; CAF-IP60; CAF1; CAF1A; CAF1P60; MPHOSPH7; MPP7

Gene Name

Homo sapiens chromatin assembly factor 1 subunit B (CHAF1B), mRNA.

Gene ID

8208

UniProt

Q13112

Conjugation

Unconjugated

Dilution

WB 1:200~1000, IHC 1:150, IF 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Transcription Factors

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

CHAF1B

Overview

Carrier-free (BSA/glycerol-free) CHAF1B mouse monoclonal antibody, clone LBI4F7

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=8208

Uniprot URL

https://www.uniprot.org/uniprot/Q13112

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