Oct4 (POU5F1) Mouse Monoclonal Antibody [Clone ID: LBI7H1]

Product Specifications

Background

This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t (6;22) (p21; q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Mar 2010]

Overview

Carrier-free (BSA/glycerol-free) POU5F1 mouse monoclonal antibody, clone LBI7H1

Synonyms

Oct-3; Oct-4; OCT3; OCT4; OTF-3; OTF3; OTF4

Gene Name

Homo sapiens POU class 5 homeobox 1 (POU5F1), transcript variant 1, mRNA.

Gene ID

5460

UniProt

Q01860

Conjugation

Unconjugated

Dilution

WB 1:200~1000, IF: 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Adult stem cells, Cancer stem cells, Embryonic stem cells, Induced pluripotent stem cells, Stem cell - Pluripotency, Transcription Factors

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.