Tyrosine Hydroxylase (TH) Mouse Monoclonal Antibody [Clone ID: LBI2E5]
Product Specifications
Background
The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]
Synonyms
DYT5b; DYT14; TYH
Gene Name
Homo sapiens tyrosine hydroxylase (TH), transcript variant 2, mRNA.
Gene ID
7054
UniProt
P07101
Conjugation
Unconjugated
Related Pathways
Metabolic pathways, Parkinson's disease, Tyrosine metabolism
Field of Research
Metabolic pathways, Parkinson's disease, Tyrosine metabolism
Dilution
WB 1:4000, IF 1:100, IHC: 1:150
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
TH
Overview
Carrier-free (BSA/glycerol-free) TH mouse monoclonal antibody, clone LBI2E5
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=7054
Uniprot URL
https://www.uniprot.org/uniprot/P07101
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