Tyrosine Hydroxylase (TH) Mouse Monoclonal Antibody [Clone ID: LBI2E5]

Product Specifications

Background

The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) TH mouse monoclonal antibody, clone LBI2E5

Synonyms

DYT5b; DYT14; TYH

Gene Name

Homo sapiens tyrosine hydroxylase (TH), transcript variant 2, mRNA.

Gene ID

7054

UniProt

P07101

Conjugation

Unconjugated

Related Pathways

Metabolic pathways, Parkinson's disease, Tyrosine metabolism

Field of Research

Metabolic pathways, Parkinson's disease, Tyrosine metabolism

Dilution

WB 1:4000, IF 1:100, IHC: 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.