P73 (TP73) Mouse Monoclonal Antibody [Clone ID: LBI2H5]
Product Specifications
Background
This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb
Synonyms
P73
Gene Name
Homo sapiens tumor protein p73 (TP73), transcript variant 1, mRNA.
Gene ID
7161
UniProt
O15350
Conjugation
Unconjugated
Related Pathways
Neurotrophin signaling pathway, p53 signaling pathway
Field of Research
Neurotrophin signaling pathway, p53 signaling pathway
Dilution
WB 1:4000, IHC 1:150, IF 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Transcription Factors
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
TP73
Overview
Carrier-free (BSA/glycerol-free) TP73 mouse monoclonal antibody, clone LBI2H5
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=7161
Uniprot URL
https://www.uniprot.org/uniprot/O15350
Curated Selection
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