P73 (TP73) Mouse Monoclonal Antibody [Clone ID: LBI2H5]

Product Specifications

Background

This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb

Overview

Carrier-free (BSA/glycerol-free) TP73 mouse monoclonal antibody, clone LBI2H5

Synonyms

P73

Gene Name

Homo sapiens tumor protein p73 (TP73), transcript variant 1, mRNA.

Gene ID

7161

UniProt

O15350

Conjugation

Unconjugated

Related Pathways

Neurotrophin signaling pathway, p53 signaling pathway

Field of Research

Neurotrophin signaling pathway, p53 signaling pathway

Dilution

WB 1:4000, IHC 1:150, IF 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Transcription Factors

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.