CD163 Mouse Monoclonal Antibody [Clone ID: LBI3D4]
Product Specifications
Background
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Synonyms
M130; MM130; SCARI1
Gene Name
Homo sapiens CD163 molecule (CD163), transcript variant 1, mRNA.
Gene ID
9332
UniProt
Q86VB7
Conjugation
Unconjugated
Dilution
WB 1:2000, IHC 1:150, IF 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Secreted Protein, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
CD163
Overview
Carrier-free (BSA/glycerol-free) CD163 mouse monoclonal antibody, clone LBI3D4
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=9332
Uniprot URL
https://www.uniprot.org/uniprot/Q86VB7
Curated Selection
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