CD105 (ENG) Mouse Monoclonal Antibody [Clone ID: LBI3D5]
Product Specifications
Background
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Synonyms
END; HHT1; ORW1
Gene Name
Homo sapiens endoglin (ENG), transcript variant 2, mRNA.
Gene ID
2022
UniProt
P17813
Conjugation
Unconjugated
Dilution
WB 1:4000, IF 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
ENG
Overview
Carrier-free (BSA/glycerol-free) ENG mouse monoclonal antibody, clone LBI3D5
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=2022
Uniprot URL
https://www.uniprot.org/uniprot/P17813
Curated Selection
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