DRP1 (DNM1L) Mouse Monoclonal Antibody [Clone ID: LBI3F3]

Product Specifications

Background

The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) DNM1L mouse monoclonal antibody, clone LBI3F3

Synonyms

DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV

Gene Name

Homo sapiens dynamin 1 like (DNM1L), transcript variant 1, mRNA.

Gene ID

10059

UniProt

O00429

Conjugation

Unconjugated

Related Pathways

Endocytosis, Fc gamma R-mediated phagocytosis

Field of Research

Endocytosis, Fc gamma R-mediated phagocytosis

Dilution

WB 1:4000, IHC 1:150, IF 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.