COPS6 Mouse Monoclonal Antibody [Clone ID: LBI2H4]
Product Specifications
Background
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. [provided by RefSeq, Jul 2008]
Synonyms
CSN6; MOV34-34KD
Gene Name
Homo sapiens COP9 signalosome subunit 6 (COPS6), mRNA.
Gene ID
10980
UniProt
Q7L5N1
Conjugation
Unconjugated
Dilution
WB 1:2000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Stem cell - Pluripotency
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
COPS6
Overview
Carrier-free (BSA/glycerol-free) COPS6 mouse monoclonal antibody, clone LBI2H4
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=10980
Uniprot URL
https://www.uniprot.org/uniprot/Q7L5N1
Curated Selection
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