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UBE2G2 Mouse Monoclonal Antibody [Clone ID: LBI9F2]

Product Specifications

Background

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jan

Synonyms

UBC7

Gene Name

Homo sapiens ubiquitin conjugating enzyme E2 G2 (UBE2G2), transcript variant 1, mRNA.

Gene ID

7327

UniProt

P60604

Conjugation

Unconjugated

Related Pathways

Parkinson's disease, Ubiquitin mediated proteolysis

Field of Research

Parkinson's disease, Ubiquitin mediated proteolysis

Dilution

WB 1:4000, IHC 1:150, IF 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

UBE2G2

Overview

Carrier-free (BSA/glycerol-free) UBE2G2 mouse monoclonal antibody, clone LBI9F2

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=7327

Uniprot URL

https://www.uniprot.org/uniprot/P60604

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