OTUB1 Mouse Monoclonal Antibody [Clone ID: LBI5B8]
Product Specifications
Background
The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
Overview
Carrier-free (BSA/glycerol-free) OTUB1 mouse monoclonal antibody, clone LBI5B8
Synonyms
HSPC263; OTB1; OTU1
Gene Name
Homo sapiens OTU deubiquitinase, ubiquitin aldehyde binding 1 (OTUB1), transcript variant 1, mRNA.
Gene ID
55611
UniProt
Q96FW1
Conjugation
Unconjugated
Dilution
WB 1:2000, IHC 1:150, FLOW 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Protease
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
OTUB1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=55611
Uniprot URL
https://www.uniprot.org/uniprot/Q96FW1
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