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Asialoglycoprotein Receptor 2 (ASGR2) Mouse Monoclonal Antibody [Clone ID: LBI2A12]

Product Specifications

Background

This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

Synonyms

ASGP-R2; ASGPR2; CLEC4H2; HBXBP; HL-2

Gene Name

Homo sapiens asialoglycoprotein receptor 2 (ASGR2), transcript variant 1, mRNA.

Gene ID

433

UniProt

P07307

Conjugation

Unconjugated

Dilution

WB 1:4000, IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

ASGR2

Overview

Carrier-free (BSA/glycerol-free) ASGR2 mouse monoclonal antibody, clone LBI2A12

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=433

Uniprot URL

https://www.uniprot.org/uniprot/P07307

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