Asialoglycoprotein Receptor 2 (ASGR2) Mouse Monoclonal Antibody [Clone ID: LBI2A12]
Product Specifications
Background
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Synonyms
ASGP-R2; ASGPR2; CLEC4H2; HBXBP; HL-2
Gene Name
Homo sapiens asialoglycoprotein receptor 2 (ASGR2), transcript variant 1, mRNA.
Gene ID
433
UniProt
P07307
Conjugation
Unconjugated
Dilution
WB 1:4000, IHC 1:150
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
ASGR2
Overview
Carrier-free (BSA/glycerol-free) ASGR2 mouse monoclonal antibody, clone LBI2A12
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=433
Uniprot URL
https://www.uniprot.org/uniprot/P07307
Curated Selection
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