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Cbl c (CBLC) Mouse Monoclonal Antibody [Clone ID: LBI3B4]

Product Specifications

Background

This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]

Overview

Carrier-free (BSA/glycerol-free) CBLC mouse monoclonal antibody, clone LBI3B4

Synonyms

CBL-3; CBL-SL; RNF57

Gene Name

Homo sapiens Cbl proto-oncogene C (CBLC), transcript variant 1, mRNA.

Gene ID

23624

UniProt

Q9ULV8

Conjugation

Unconjugated

Related Pathways

Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Insulin signaling pathway, Jak-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Ubiquitin mediated proteolysis

Field of Research

Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Insulin signaling pathway, Jak-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Ubiquitin mediated proteolysis

Dilution

WB 1:500, FLOW 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

CBLC

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=23624

Uniprot URL

https://www.uniprot.org/uniprot/Q9ULV8

Frequently Asked Questions

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