ERp57 (PDIA3) Mouse Monoclonal Antibody [Clone ID: LBI4D7]

Product Specifications

Background

This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) PDIA3 mouse monoclonal antibody, clone LBI4D7

Synonyms

ER60; ERp57; ERp60; ERp61; GRP57; GRP58; HEL-S-93n; HEL-S-269; HsT17083; P58; PI-PLC

Gene Name

Homo sapiens protein disulfide isomerase family A member 3 (PDIA3), mRNA.

Gene ID

2923

UniProt

P30101

Conjugation

Unconjugated

Related Pathways

Antigen processing and presentation

Field of Research

Antigen processing and presentation

Dilution

WB 1:1000, IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.