UBC6e (UBE2J1) Mouse Monoclonal Antibody [Clone ID: LBI3D5]
Product Specifications
Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system. [provided by RefSeq, Jul 2008]
Overview
Carrier-free (BSA/glycerol-free) UBE2J1 mouse monoclonal antibody, clone LBI3D5
Synonyms
CGI-76; HSPC153; HSPC205; HSU93243; NCUBE-1; NCUBE1; UBC6; UBC6E; Ubc6p
Gene Name
Homo sapiens ubiquitin conjugating enzyme E2 J1 (UBE2J1), mRNA.
Gene ID
51465
UniProt
Q9Y385
Conjugation
Unconjugated
Related Pathways
Parkinson's disease, Ubiquitin mediated proteolysis
Field of Research
Parkinson's disease, Ubiquitin mediated proteolysis
Dilution
WB 1:2000, IHC 1:150
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
UBE2J1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=51465
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y385
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