UBC6e (UBE2J1) Mouse Monoclonal Antibody [Clone ID: LBI1H10]

Product Specifications

Background

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.

Overview

Carrier-free (BSA/glycerol-free) UBE2J1 mouse monoclonal antibody, clone LBI1H10

Synonyms

CGI-76; HSPC153; HSPC205; HSU93243; NCUBE-1; NCUBE1; UBC6; UBC6E; Ubc6p

Gene Name

Homo sapiens ubiquitin conjugating enzyme E2 J1 (UBE2J1), mRNA.

Gene ID

51465

UniProt

Q9Y385

Conjugation

Unconjugated

Related Pathways

Parkinson's disease, Ubiquitin mediated proteolysis

Field of Research

Parkinson's disease, Ubiquitin mediated proteolysis

Dilution

WB 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.