RFC2 Mouse Monoclonal Antibody [Clone ID: LBI4E1]
Product Specifications
Background
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) . RFC, also called activator 1, is a protein complex consisting of five distinct subunits of 145, 40, 38, 37, and 36.5 kD. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP. Deletion of this gene has been associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Synonyms
RFC40
Gene Name
Homo sapiens replication factor C subunit 2 (RFC2), transcript variant 2, mRNA.
Gene ID
5982
UniProt
P35250
Conjugation
Unconjugated
Related Pathways
DNA replication, Mismatch repair, Nucleotide excision repair
Field of Research
DNA replication, Mismatch repair, Nucleotide excision repair
Dilution
WB 1:200~2000, FLOW 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Stem cell - Pluripotency
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
RFC2
Overview
Carrier-free (BSA/glycerol-free) RFC2 mouse monoclonal antibody, clone LBI4E1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5982
Uniprot URL
https://www.uniprot.org/uniprot/P35250
Curated Selection
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