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Phosphoribosyl pyrophosphate amidotransferase (PPAT) Mouse Monoclonal Antibody [Clone ID: LBI3C6]

Product Specifications

Background

The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.

Overview

Carrier-free (BSA/glycerol-free) PPAT mouse monoclonal antibody, clone LBI3C6

Synonyms

ATASE; GPAT; PRAT

Gene Name

Homo sapiens phosphoribosyl pyrophosphate amidotransferase (PPAT), transcript variant 1, mRNA.

Gene ID

5471

UniProt

Q06203

Conjugation

Unconjugated

Related Pathways

Alanine, aspartate and glutamate metabolism, Metabolic pathways, Purine metabolism

Field of Research

Alanine, aspartate and glutamate metabolism, Metabolic pathways, Purine metabolism

Dilution

WB 1:200 - 1:1000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Protease

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

PPAT

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=5471

Uniprot URL

https://www.uniprot.org/uniprot/Q06203

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