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Kv beta 1 (KCNAB1) Mouse Monoclonal Antibody [Clone ID: LBI9F7]

Product Specifications

Background

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s) . This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes three distinct isoforms which are encoded by three alternatively spliced transcript variants of this gene. These three isoforms are beta subunits, which form heteromultimeric complex with alpha subunits and modulate the activity of the pore-forming alpha subunits. [provided by RefSeq]

Overview

Carrier-free (BSA/glycerol-free) KCNAB1 mouse monoclonal antibody, clone LBI9F7

Synonyms

AKR6A3; hKvb3; hKvBeta3; KCNA1B; KV-BETA-1; Kvb1.3

Gene Name

Homo sapiens potassium voltage-gated channel subfamily A regulatory beta subunit 1 (KCNAB1), transcript variant 3, mRNA.

Gene ID

7881

UniProt

Q14722

Conjugation

Unconjugated

Dilution

WB 1:2000, IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Ion Channels: Other

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

KCNAB1

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=7881

Uniprot URL

https://www.uniprot.org/uniprot/Q14722

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