RbAp46 (RBBP7) Mouse Monoclonal Antibody [Clone ID: LBI3A12]

Product Specifications

Background

This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Overview

Carrier-free (BSA/glycerol-free) RBBP7 mouse monoclonal antibody, clone LBI3A12

Synonyms

RbAp46

Gene Name

Homo sapiens RB binding protein 7, chromatin remodeling factor (RBBP7), transcript variant 2, mRNA.

Gene ID

5931

UniProt

Q16576

Conjugation

Unconjugated

Dilution

WB 1:2000, IF 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.