PTPN7 Mouse Monoclonal Antibody [Clone ID: LBI3B10]

Product Specifications

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]

Overview

Carrier-free (BSA/glycerol-free) PTPN7 mouse monoclonal antibody, clone LBI3B10

Synonyms

BPTP-4; HEPTP; LC-PTP; LPTP; PTPNI

Gene Name

Homo sapiens protein tyrosine phosphatase non-receptor type 7 (PTPN7), transcript variant 2, mRNA.

Gene ID

5778

UniProt

P35236

Conjugation

Unconjugated

Related Pathways

MAPK signaling pathway

Field of Research

MAPK signaling pathway

Dilution

WB 1:500~2000, IF 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Phosphatase

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.