UNG Mouse Monoclonal Antibody [Clone ID: LBI1A11]
Product Specifications
Background
This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq]
Synonyms
DGU; HIGM4; HIGM5; UDG; UNG1; UNG2; UNG15
Gene Name
Homo sapiens uracil DNA glycosylase (UNG), transcript variant 2, mRNA.
Gene ID
7374
UniProt
P13051
Conjugation
Unconjugated
Related Pathways
Base excision repair, Primary immunodeficiency
Field of Research
Base excision repair, Primary immunodeficiency
Dilution
WB 1:2000, IHC 1:150, IF 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Stem cell - Pluripotency
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
UNG
Overview
Carrier-free (BSA/glycerol-free) UNG mouse monoclonal antibody, clone LBI1A11
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=7374
Uniprot URL
https://www.uniprot.org/uniprot/P13051
Curated Selection
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