PNPO Mouse Monoclonal Antibody [Clone ID: LBI1H9]
Product Specifications
Background
The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.
Overview
Carrier-free (BSA/glycerol-free) PNPO mouse monoclonal antibody, clone LBI1H9
Synonyms
HEL-S-302; PDXPO
Gene Name
Homo sapiens pyridoxamine 5'-phosphate oxidase (PNPO), mRNA.
Gene ID
55163
UniProt
Q9NVS9
Conjugation
Unconjugated
Related Pathways
Metabolic pathways, Vitamin B6 metabolism
Field of Research
Metabolic pathways, Vitamin B6 metabolism
Dilution
WB 1:500, IHC 1:150
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PNPO
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=55163
Uniprot URL
https://www.uniprot.org/uniprot/Q9NVS9
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