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COASY Mouse Monoclonal Antibody [Clone ID: LBI2H1]

Product Specifications

Background

Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. COASY is a bifunctional enzyme that catalyzes the 2 last steps in CoA synthesis. These activities are performed by 2 separate enzymes, phosphopantetheine adenylyltransferase (PPAT; EC 2.7.7.3) and dephospho-CoA kinase (DPCK; EC 2.7.1.24), in prokaryotes (Daugherty et al., 2002 [PubMed 11923312]) . [supplied by OMIM]

Synonyms

DPCK; NBIA6; NBP; pOV-2; PPAT; UKR1

Gene Name

Homo sapiens Coenzyme A synthase (COASY), transcript variant 1, mRNA.

Gene ID

80347

UniProt

Q13057

Conjugation

Unconjugated

Related Pathways

Metabolic pathways, Pantothenate and CoA biosynthesis

Field of Research

Metabolic pathways, Pantothenate and CoA biosynthesis

Dilution

WB 1:2000, IHC 1:150, FLOW 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

COASY

Overview

Carrier-free (BSA/glycerol-free) COASY mouse monoclonal antibody, clone LBI2H1

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=80347

Uniprot URL

https://www.uniprot.org/uniprot/Q13057

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