PDE1B Mouse Monoclonal Antibody [Clone ID: LBI6E4]

Product Specifications

Background

Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1B, are calmodulin (see MIM 114180) -dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]) . [supplied by OMIM]

Overview

Carrier-free (BSA/glycerol-free) PDE1B mouse monoclonal antibody, clone LBI6E4

Synonyms

PDE1B1; PDES1B

Gene Name

Homo sapiens phosphodiesterase 1B (PDE1B), transcript variant 1, mRNA.

Gene ID

5153

UniProt

Q01064

Conjugation

Unconjugated

Related Pathways

Calcium signaling pathway, Progesterone-mediated oocyte maturation, Purine metabolism

Field of Research

Calcium signaling pathway, Progesterone-mediated oocyte maturation, Purine metabolism

Dilution

WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.