XPF (ERCC4) Mouse Monoclonal Antibody [Clone ID: LBI1B2]

Product Specifications

Background

The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6) .

Overview

Carrier-free (BSA/glycerol-free) ERCC4 mouse monoclonal antibody, clone LBI1B2

Synonyms

ERCC11; FANCQ; RAD1; XFEPS; XPF

Gene Name

Homo sapiens ERCC excision repair 4, endonuclease catalytic subunit (ERCC4), mRNA.

Gene ID

2072

UniProt

Q92889

Conjugation

Unconjugated

Related Pathways

Nucleotide excision repair

Field of Research

Nucleotide excision repair

Dilution

WB 1:500, IF 1:100, FLOW 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.