XPF (ERCC4) Mouse Monoclonal Antibody [Clone ID: LBI1B2]
Product Specifications
Background
The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6) .
Overview
Carrier-free (BSA/glycerol-free) ERCC4 mouse monoclonal antibody, clone LBI1B2
Synonyms
ERCC11; FANCQ; RAD1; XFEPS; XPF
Gene Name
Homo sapiens ERCC excision repair 4, endonuclease catalytic subunit (ERCC4), mRNA.
Gene ID
2072
UniProt
Q92889
Conjugation
Unconjugated
Related Pathways
Nucleotide excision repair
Field of Research
Nucleotide excision repair
Dilution
WB 1:500, IF 1:100, FLOW 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
ERCC4
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=2072
Uniprot URL
https://www.uniprot.org/uniprot/Q92889
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