STAT4 Mouse Monoclonal Antibody [Clone ID: LBI2G5]

Product Specifications

Background

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug

Overview

Carrier-free (BSA/glycerol-free) STAT4 mouse monoclonal antibody, clone LBI2G5

Synonyms

SLEB11

Gene Name

Homo sapiens signal transducer and activator of transcription 4 (STAT4), transcript variant 1, mRNA.

Gene ID

6775

UniProt

Q14765

Conjugation

Unconjugated

Related Pathways

Jak-STAT signaling pathway

Field of Research

Jak-STAT signaling pathway

Dilution

WB 1:2000, IF 1:100, FLOW 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Transcription Factors

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.