PRKAR1B Mouse Monoclonal Antibody [Clone ID: LBI2A3]
Product Specifications
Background
Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP. [supplied by OMIM, Jun 2009]
Overview
Carrier-free (BSA/glycerol-free) PRKAR1B mouse monoclonal antibody, clone LBI2A3
Synonyms
PRKAR1
Gene Name
Homo sapiens protein kinase cAMP-dependent type I regulatory subunit beta (PRKAR1B), transcript variant 2, mRNA.
Gene ID
5575
UniProt
P31321
Conjugation
Unconjugated
Related Pathways
Apoptosis, Insulin signaling pathway
Field of Research
Apoptosis, Insulin signaling pathway
Dilution
WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PRKAR1B
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5575
Uniprot URL
https://www.uniprot.org/uniprot/P31321
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