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PRKAR1B Mouse Monoclonal Antibody [Clone ID: LBI2A3]

Product Specifications

Background

Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP. [supplied by OMIM, Jun 2009]

Overview

Carrier-free (BSA/glycerol-free) PRKAR1B mouse monoclonal antibody, clone LBI2A3

Synonyms

PRKAR1

Gene Name

Homo sapiens protein kinase cAMP-dependent type I regulatory subunit beta (PRKAR1B), transcript variant 2, mRNA.

Gene ID

5575

UniProt

P31321

Conjugation

Unconjugated

Related Pathways

Apoptosis, Insulin signaling pathway

Field of Research

Apoptosis, Insulin signaling pathway

Dilution

WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

PRKAR1B

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=5575

Uniprot URL

https://www.uniprot.org/uniprot/P31321

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