LNK (SH2B3) Mouse Monoclonal Antibody [Clone ID: LBI6F11]

Product Specifications

Background

This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus.

Overview

Carrier-free (BSA/glycerol-free) SH2B3 mouse monoclonal antibody, clone LBI6F11

Synonyms

IDDM20; LNK

Gene Name

Homo sapiens SH2B adaptor protein 3 (SH2B3), transcript variant 1, mRNA.

Gene ID

10019

UniProt

Q9UQQ2

Conjugation

Unconjugated

Related Pathways

Neurotrophin signaling pathway

Field of Research

Neurotrophin signaling pathway

Dilution

WB 1:2000, FLOW 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.