DCK Mouse Monoclonal Antibody [Clone ID: LBI3F5]
Product Specifications
Background
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008]
Synonyms
MGC117410; MGC138632
Gene Name
Homo sapiens deoxycytidine kinase (DCK), mRNA.
Gene ID
1633
UniProt
P27707
Conjugation
Unconjugated
Related Pathways
Purine metabolism, Pyrimidine metabolism
Field of Research
Purine metabolism, Pyrimidine metabolism
Dilution
WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
DCK
Overview
Carrier-free (BSA/glycerol-free) DCK mouse monoclonal antibody, clone LBI3F5
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=1633
Uniprot URL
https://www.uniprot.org/uniprot/P27707
Curated Selection
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