DCK Mouse Monoclonal Antibody [Clone ID: LBI3F5]

Product Specifications

Background

Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) DCK mouse monoclonal antibody, clone LBI3F5

Synonyms

MGC117410; MGC138632

Gene Name

Homo sapiens deoxycytidine kinase (DCK), mRNA.

Gene ID

1633

UniProt

P27707

Conjugation

Unconjugated

Related Pathways

Purine metabolism, Pyrimidine metabolism

Field of Research

Purine metabolism, Pyrimidine metabolism

Dilution

WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.